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排序方式: 共有194条查询结果,搜索用时 687 毫秒
1.
IntroductionWiththedevelopmentandapplicationofnewpesticide ,insecticidehasgreatlyreducedtheharmofpesttocrops .Bifenthrinisaneffectivepyrethroidinsecticideandacaricideagainstawiderangeofinsectpests ,anditisverypoisonoustomammal,aquatic .Thisinsecticideiswi… 相似文献
2.
苯胺类化合物在不同pH值下对大型蚤的急性毒性及QSAR研究 总被引:6,自引:0,他引:6
测定了13种苯胺类化合物在不同pH下(6.0,7.8,9.0)对大型蚤(Daphnia magna)的24h半数活动抑制浓度24h-1C50,应用三种理化参数logP,TSA和pKa,对毒性数据进行了定量构效关系(QSARs)研究,并在此基础上初步探讨了苯胺类化合物的毒性机制。 相似文献
3.
Hela Toumi Karen F. Burga-Perez Jean-François Ferard 《Journal of environmental science and health. Part. B》2016,51(1):57-62
The ecotoxic effects of carbaryl (carbamate insecticide) were investigated with a battery of four aquatic bioassays. The nominal effective concentrations immobilizing 50% of Daphnia magna (EC50) after 24 and 48 h were 12.76 and 7.47 µg L?1, respectively. After 21 days of exposure of D. magna, LOECs (lowest observed effect concentrations) for cumulative molts and the number of neonates per surviving adult were observed at carbaryl concentration of 0.4 µg L?1. An increase of embryo deformities (curved or unextended shell spines) was observed at 1.8 and 3.7 µg L?1, revealing that carbaryl could act as an endocrine disruptor in D. magna. Other bioassays of the tested battery were less sensitive: the IC50-72h and IC10-72h of the algae Pseudokirchneriella subcapitata were 5.96 and 2.87 mg L?1, respectively. The LC50-6d of the ostracod Heterocypris incongruens was 4.84 mg L?1. A growth inhibition of H. incongruens was registered after carbaryl exposure and the IC20-6d was 1.29 mg L?1. Our results suggest that the daphnid test sensitivity was better than other used tests. Moreover, carbaryl has harmful and toxic effects on tested species because it acts at low concentrations on diverse life history traits of species and induce embryo deformities in crustaceans. 相似文献
4.
大型蚤是一种国际公认的标准实验生物,广泛应用于污水、地表水等水质毒性检测。毒性水平较低的城市二级出水,对大型蚤往往无急性毒性效应,而具有慢性毒性效应,但慢性毒性检测周期过长,因此探索一种更灵敏的指标,实现快速检测,对于控制二级出水的水质风险具有重要意义。本研究考察了大型蚤在短期暴露于城市二级出水条件下,其体内乙酰胆碱酯酶、超氧化物歧化酶、过氧化氢酶、ATP酶、羧酸酯酶和碱性磷酸酯酶的酶活变化特征,从中筛选出对二级出水毒性响应灵敏的标志酶指标。实验结果表明,碱性磷酸酯酶、过氧化氢酶对二级出水毒性响应相对较灵敏,具有成为标志酶的潜力,研究结果为城市二级出水生物毒性评价方法优化提供新的思路。 相似文献
5.
大型溞母溞暴露于氨氮所产子代对氨氮毒性的耐受性 总被引:2,自引:0,他引:2
采用大型溞(Daphnia magna)作为受试生物,在测定了氨氮对大型溞的急慢性毒性效应的基础上,进一步研究了在慢性毒性试验中暴露于氨氮环境下的母溞所产子代对氨氮的毒性响应.急性毒性试验结果表明,氨氮对大型溞的24 h和48 h的LC50分别为165.97和69.54 mg/L.21 d慢性试验结果表明:大型溞的生长指标——脱皮数是对氨氮最为敏感的毒性参数;其慢性毒性下限值(LCL)和慢性毒性上限值(UCL)分别为1.88和3.75 mg/L;据此计算出的慢性毒性值(CHV)为2.66 mg/L,急慢性比(ACR)为26.14.在慢性试验中,暴露于毒物的母体所产的子代幼溞,与对照组相比,其48 h LC50都有所增大(增幅为13.7%~56.2%),说明对毒物的适应性有所增强. 相似文献
6.
7.
Organic solvents, such as dimethylsulfoxide (DMSO) and methanol are widely used as vehicles to solubilise lipophilic test compounds in toxicity testing. However, the effects of such solvents upon innate detoxification processes in aquatic organisms are poorly understood. This study assessed the effect of solvent exposure upon cytochrome P450 (CYP)-mediated xenobiotic metabolism in Daphnia magna and zebrafish larvae (4 d post fertilisation). Adult D. magna were demonstrated to have a low, but detectable, metabolism of ethoxyresorufin in vivo and this activity was not modulated by pre-exposure to DMSO or methanol (24 h, up to 0.1% and 0.05% v/v, respectively). In contrast, the metabolism of ethoxyresorufin in zebrafish larvae was significantly reduced by both solvents (0.1% and 0.05% v/v, respectively) after 24 h of exposure. In zebrafish, these observed decreases in activity towards ethoxyresorufin were accompanied by decreased expression of a variety of genes coding for drug metabolising enzymes (corresponding to CYP1, CYP2, CYP3 and UDP-glucuronyl transferase [UGT] family enzymes), measured by quantitative PCR. Reduction of gene expression and CYP1 enzyme activities by methanol (0.05% v/v) in zebrafish larvae was partially reversed by co-exposure with Aroclor 1254 (100 μg L−1). Overall this study suggests that relatively low concentrations of organic solvents can impact upon the biotransformation of certain xenobiotics in zebrafish larvae, and that this warrants consideration when assessing compounds for metabolism and toxicity in this species. 相似文献
8.
There is the need to integrate existing toxicity data in a coherent framework for extending their domain of applicability as well as their extrapolation potential. This integration would also reduce time and cost-consuming aspects of these tests and reduce animal usage. In this work, based on data extracted from literature, we have assessed the advantages that a dynamic biology-toxicant fate coupled model for Daphnia magna could provide when assessing toxicity data, in particular, the possibility to obtain from short-term (acute) toxicity test long-term (chronic) toxicity values taking into account the inherent variability of D. magna populations and the multiple sources of data. The results show that this approach overcomes some of the limitations of existing toxicity tests and that the prediction errors are considerably reduced when compared with the factor from 2 to 5 obtained using acute-to-chronic ratios. 相似文献
9.
10.
兰州大石鸡不同生活史阶段栖息地选择的初步研究 总被引:8,自引:0,他引:8
大石鸡不同生活史阶段选择不同的栖息地.集群期选择坡度小、低海拔、东向的山坡和坟地.配对期选择坡度30~60°、海拔居中的栖息地,选择的栖息地范围较宽.产卵期多见于坡度小、地面环境异质性小、海拔高的农田和山坡.育雏期选择植物丛密度低、坡度小、海拔高的山坡和农田.繁殖后期选择植物丛密度低、低海拔、东向的山坡和沟底.不同生活史阶段植被覆盖度、植物高度、环境类型和坡向差异不显著,坡度差异显著,植物丛密度、海拔高度和地面环境异质性差异极显著.在各环境因子中,只有地面环境异质性对大石鸡栖息地选择的影响较显著.地形、食物和气候可能是影响大石鸡栖息地选择的根本因素. 相似文献